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The Reaction of Cyclohexan-1,3-dione with Cyanomethylenes: Synthesis of Thiophenes and Their Fused Derivatives with Antifungal Activities
Journal article   Peer reviewed

The Reaction of Cyclohexan-1,3-dione with Cyanomethylenes: Synthesis of Thiophenes and Their Fused Derivatives with Antifungal Activities

Rafat M. Mohareb, Sherif M. Sherif and Hosam El-Dean Moustafa
Phosphorus, sulfur, and silicon and the related elements, Vol.184(8), pp.2078-2096
06/08/2009

Abstract

Chemistry Chemistry, Inorganic & Nuclear Chemistry, Organic Physical Sciences Science & Technology
2-Amino-7-oxotetrahydrobenzo[b]thiophenes 3a,b were prepared according to the Gewald procedure. Their reactivity toward a variety of chemical reagents was studied to give annulated heterocycles with potential bio-responses.

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