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The Synthesis of New Spiro β-Lactam and Thiazolidinone Compounds Incorporating Quinones and Their Biological Activity
Journal article   Peer reviewed

The Synthesis of New Spiro β-Lactam and Thiazolidinone Compounds Incorporating Quinones and Their Biological Activity

A. K. Khalafallah, N. A. A. El-Kanzi, H. A. Soleiman, M. Younis and Islam Helmy El-Azab
Phosphorus, sulfur, and silicon and the related elements, Vol.181(11), pp.2483-2503
01/11/2006

Abstract

Spiro β-lactam thiazolidinone
A series of some fused and spiro heterocyclic compounds such as pyrazolines, isoxazolines, pyrimidines, β-lactams, and thiazolidinone derivatives incorporating compounds 3, 6a-d, 7a-d, 9a-c, 10a-c, 11a-c, 12a-c, and 13a-c have been synthesized by a cycloaddition and cyclocondensation reaction of monochloroacetyl chloride, mercaptoacetic acid, hydrazines, hydroxylamine, urea, and thiourea with the prepared 5a-d and 8a-c.

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