Abstract
The heterocyclization of an asymmetrical N,N′-disubstituted thiourea (1a-d) in ring closure reactions with Br
2
/AcOH, ethyl chloroacetate, diethyl oxalate, diethyl malonate, and hydrazine hydrate led to the direct formation of sulfur-bearing various heterocyclic systems (2-8) in which the thiaenolization is toward the aryl group. The synthetic work and reactivity investigations have been well supported by standard modern spectroscopic techniques (IR,
1
H NMR,
13
C NMR, mass spectrum, and microanalysis).