Abstract
The aim of this study is to investigate the protective effect of royal jelly (RJ) against Aluminum Chloride (AlCl3) toxicity on Pituitary, Thyroid and Sex Hormones in addition to histological sections of testis. The animals were given a dose of Aluminum Chloride (AlCl3) (30mg/kg) every other day intraperitoneally for eight weeks, and a dose of Royal jelly (RJ) (400mg/kg) daily in drinking water for eight weeks. Follicle stimulating hormone (FSH), luteinizing hormone (LH), thyroid stimulating hormone (TSH), thyroxin (T4), triiodothyronine (T3), percentage of triiodothyronine to thyroxin (T3/T4) and testosterone level were measured in blood serum. AlCl3 caused a significant decrease of FSH, LH, TSH, T4, T3, T3/T4 and testosterone, and caused the development of oligospermia, hypoplasia, congested blood vessel and exfoliated tubules in the testis, but royal jelly attenuates these effects.