Abstract
A total 560 day-old broiler chicks (Ross 308) was randomly allocated to seven treatments (eight replicates). Control (basal diet), T1, infected with Clostridium perfringens, T2, infected + Avilamycin at the rate of 0.2 g/kg T3, infected + essential oil of thyme, T4, infected + Sanguinarine, T5, infected + Anti-Salmonella phytobiotic, T6., infected + essential oils of thyme, anise and others (oregano, carvacol, yucca extract and cinnamaldehyde). Feed conversion ratio (FCR) were significantly (P<0.05) high in the T2 during the third week. The dressing percentage decreased significantly (P<0.05) and intestinal weight increased (P<0.05) in T1. Blood protein, and globulin increased significantly (P<0.05) in birds in T6 during fourth weeks, while blood alanine transaminase (ALT) increased significantly (P<0.05) in T5. Thiobarbituric acid reactive substances (TBARS) increased significantly (P<0.05) in T5 and T6. Similarly, villus height and width increased significantly (P<0.05) in T5 and T6. From the results of the present study, it was concluded that different feed additives could be substituted with antibiotics in the feed of broiler exposed to Clostridium perfringens challenge.