Abstract
α-Aminocarbanions are important synthetic intermediates in modern organic synthesis. Due to the difficult generation of the non-stabilized α-aminocarbanions, stabilized α-aminocarbanions have been employed in the most synthetic applications. However, in many cases, two steps (protection and deprotection) could be saved by using non-stabilized α-aminocarbanions for the same process. This report discussed important recent progress in the generation of the non-stabilized α-aminocarbanions, and will hopefully stimulate the further use of non-stabilized α-aminocarbanions in synthesis. The physical properties and reactivities of non-stabilized α-aminocarbanions were also presented.