The global burden of childhood and adolescent cancer in 2017: an analysis of the Global Burden of Disease Study 2017

Lisa M. Force; Ibrahim Abdollahpour; Shailesh M. Advani; Dominic Agius; Elham Ahmadian; Fares Alahdab; Tahiya Alam; Animut Alebel; Vahid Alipour; Christine A. Allen; Amir Almasi-Hashiani; Elysia M. Alvarez; Saeed Amini; Yaw Ampem Amoako; Nahla Hamed Anber; Jalal Arabloo; Al Artaman; Suleman Atique; Ashish Awasthi; Mojtaba Bagherzadeh; Huda Basaleem; Eyasu Tamru Bekru; Ali Bijani; Kassawmar Angaw Bogale; Mate Car; Felix Carvalho; Clara Castro; Ferran Catala-Lopez; Dinh-Toi Chu; Vera M. Costa; Amira Hamed Darwish; Feleke Mekonnen Demeke; Asmamaw Bizuneh Demis; Gebre Teklemariam Demoz; Samath Dhamminda Dharmaratne; Huyen Phuc Do; Linh Phuong Doan; Manisha Dubey; Aziz Eftekhari; Ziad El-Khatib; Mohammad Hassan Emamian; Mahdieh Abbasalizad Farhangi; Eduarda Fernandes; Florian Fischer; Reza Fouladi Fard; Paola M. Friedrich; Takeshi Fukumoto; Getnet Azeze Gedefaw; Ahmad Ghashghaee; Asadollah Gholamian; Arvin Haj-Mirzaian; Arya Haj-Mirzaian; Samer Hamidi; James D. Harvey; Hamid Yimam Hassen; Simon Hay; Chi Linh Hoang; Michael K. Hole; Nobuyuki Horita; Seyyed Nasrollah Hosseini; Mehdi Hosseinzadeh; Mohamed Hsairi; Melissa Maria Hudson; Kaire Innos; Farzad Jalilian; Spencer L. James; Amir Kasaeian; Tesfaye Dessale Kassa; Nicholas J. Kassebaum; Peter Njenga Keiyoro; Yousef Saleh Khader; Jagdish Khubchandani; Neda Kianipour; Jeannette Kirby; Adnan Kisa; Sezer Kisa; Jonathan M. Kocarnik; Paolo Lauriola; Alan D. Lopez; Margit Magi; Manzoor Ahmad Malik; Ali Manafi; Navid Manafi; Mohammad Ali Mansournia; Benjamin Ballard Massenburg; Varshil Mehta; Hagazi Gebre Meles; Tuomo J. Meretoja; Tomislav Mestrovic; Mehdi Mirzaei-Alavijeh; Seyed Mostafa Mir; Dara K. Mohammad; Aso Mohammad Darwesh; Naser Mohammad Gholi Mezerji; Roghayeh Mohammadibakhsh; Milad Mohammadoo-Khorasani; Ali H. Mokdad; Yoshan Moodley; Mahmood Moosazadeh; Maryam Moossavi; Farhad Moradpour; Shane Douglas Morrison; Kindie Fentahun Muchie; Mohsen Naghavi; Javad Nazari; Josephine W. Ngunjiri; Cuong Tat Nguyen; Long Hoang Nguyen; Son Hoang Nguyen; Trang Huyen Nguyen; Molly R. Nixon; Andrew T. Olagunju; Tinuke O. Olagunju; Sok King Ong; Keiu Paapsi; Alyssa Pennini; David M. Pereira; Julian David Pillay; Mostafa Qorbani; Mohammad Rabiee; Navid Rabiee; Samira Raoofi; David Laith Rawaf; Salman Rawaf; Robert C. Reiner; Nima Rezaei; Aziz Rezapour; Kedir Teji Roba; Les L. Robison; Carlos Rodriguez-Galindo; Gholamreza Roshandel; Saeid Safiri; Mohamadreza Salahshoor; Saleh Salehi Zahabi; Abdallah M. Samy; Milena M. Santric Milicevic; Maheswar Satpathy; Susan M. Sawyer; Seyedmojtaba Seyedmousavi; Hosein Shabaninejad; Masood Ali Shaikh; Amir Shamshirian; Morteza Shamsizadeh; Reza Shirkoohi; Soraya Siabani; Jasvinder A. Singh; Khairil Siramlee; Rafael Tabares-Seisdedos; Mohamad-Hani Temsah; Bach Xuan Tran; Irfan Ullah; Amir Vahedian-Azimi; Stein Emil Vollset; Theo Vos; Yasir Waheed; Girmay Teklay Weldesamuel; Hailemariam Mekonnen Workie; Rixing Xu; Mehdi Yaseri; Naohiro Yonemoto; Chuanhua Yu; Vesna Zadnik; Telma Zahirian Moghadam; Zoubida Zaidi; Alireza Zangeneh; Taye Abuhay Zewale; Arash Ziapour; Sanjay Zodpey; Christopher J. L. Murray; Christina Fitzmaurice; Nickhill Bhakta; GBD 2017 Childhood Canc Collaborat

doi:10.1016/S1470-2045(19)30339-0

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The global burden of childhood and adolescent cancer in 2017: an analysis of the Global Burden of Disease Study 2017

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The global burden of childhood and adolescent cancer in 2017: an analysis of the Global Burden of Disease Study 2017

Lisa M. Force, Ibrahim Abdollahpour, Shailesh M. Advani, Dominic Agius, Elham Ahmadian, Fares Alahdab, Tahiya Alam, Animut Alebel, Vahid Alipour, Christine A. Allen, …

The lancet oncology, Vol.20(9), pp.1211-1225

01/09/2019

DOI: https://doi.org/10.1016/S1470-2045(19)30339-0

PMCID: PMC6722045

PMID: 31371206

Abstract

Life Sciences & Biomedicine

Oncology

Science & Technology

Background Accurate childhood cancer burden data are crucial for resource planning and health policy prioritisation. Model-based estimates are necessary because cancer surveillance data are scarce or non-existent in many countries. Although global incidence and mortality estimates are available, there are no previous analyses of the global burden of childhood cancer represented in disability-adjusted life-years (DALYs). Methods Using the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2017 methodology, childhood (ages 0-19 years) cancer mortality was estimated by use of vital registration system data, verbal autopsy data, and population-based cancer registry incidence data, which were transformed to mortality estimates through modelled mortality-to-incidence ratios (MIRs). Childhood cancer incidence was estimated using the mortality estimates and corresponding MIRs. Prevalence estimates were calculated by using MIR to model survival and multiplied by disability weights to obtain years lived with disability (YLDs). Years of life lost (YLLs) were calculated by multiplying age-specific cancer deaths by the difference between the age of death and a reference life expectancy. DALYs were calculated as the sum of YLLs and YLDs. Final point estimates are reported with 95% uncertainty intervals. Findings Globally, in 2017, there were 11.5 million (95% uncertainty interval 10.6-12.3) DALYs due to childhood cancer, 97.3% (97.3-97.3) of which were attributable to YLLs and 2.7% (2.7-2.7) of which were attributable to YLDs. Childhood cancer was the sixth leading cause of total cancer burden globally and the ninth leading cause of childhood disease burden globally. 82.2% (82.1-82.2) of global childhood cancer DALYs occurred in low, low-middle, or middle Socio-demographic Index locations, whereas 50.3% (50.3-50.3) of adult cancer DALYs occurred in these same locations. Cancers that are uncategorised in the current GBD framework comprised 26.5% (26.5-26.5) of global childhood cancer DALYs. Interpretation The GBD 2017 results call attention to the substantial burden of childhood cancer globally, which disproportionately affects populations in resource-limited settings. The use of DALY-based estimates is crucial in demonstrating that childhood cancer burden represents an important global cancer and child health concern. (C) 2019 The Author(s). Published by Elsevier Ltd.

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Title: The global burden of childhood and adolescent cancer in 2017: an analysis of the Global Burden of Disease Study 2017
Creators - without role: Lisa M. Force - St Jude Childrens Res Hosp, Dept Oncol, 332 N Lauderdale St, Memphis, TN 38105 USA
Ibrahim Abdollahpour - Arak University
Shailesh M. Advani - NIH, Social Behav Res Branch, Bldg 10, Bethesda, MD 20892 USA
Dominic Agius - Directorate Hlth Informat & Res, Dept Hlth, Pieta, Malta
Elham Ahmadian - College Station Medical Center
Fares Alahdab - Evidence
Tahiya Alam - University of Washington
Animut Alebel - Debre Markos University
Vahid Alipour - College Station Medical Center
Christine A. Allen - University of Washington
Amir Almasi-Hashiani - Arak University
Elysia M. Alvarez - Univ Calif Davis, Dept Pediat, Sacramento, CA 95817 USA
Saeed Amini - Arak University
Yaw Ampem Amoako - College Station Medical Center
Nahla Hamed Anber - Mansoura University
Jalal Arabloo - College Station Medical Center
Al Artaman - University of Manitoba
Suleman Atique - University of Lahore
Ashish Awasthi - Indian Inst Publ Hlth, Gandhinagar, India
Mojtaba Bagherzadeh - Sharif University of Technology
Huda Basaleem - University of Aden
Eyasu Tamru Bekru - Wolaita Sodo University
Ali Bijani - College Station Medical Center
Kassawmar Angaw Bogale - Clin Pharm Unit, Mekelle, Ethiopia
Mate Car
Felix Carvalho - Minist Hlth, Zagreb, Croatia
Clara Castro - Portuguese Oncol Inst Porto, Dept Epidemiol, Porto, Portugal
Ferran Catala-Lopez - Supreme Council Of Health
Dinh-Toi Chu - Hanoi Natl Univ Educ, Fac Biol, Hanoi, Vietnam
Vera M. Costa - Universidade do Porto
Amira Hamed Darwish - College Station Medical Center
Feleke Mekonnen Demeke - College Station Medical Center
Asmamaw Bizuneh Demis - Woldia University
Gebre Teklemariam Demoz - Aksum University
Samath Dhamminda Dharmaratne - University of Washington
Huyen Phuc Do - Trường ĐH Nguyễn Tất Thành
Linh Phuong Doan - NCD Prevent & Control Unit, Zagreb, Croatia
Manisha Dubey - World Food Programme
Aziz Eftekhari - College Station Medical Center
Ziad El-Khatib - Karolinska Institutet
Mohammad Hassan Emamian - College Station Medical Center
Mahdieh Abbasalizad Farhangi - College Station Medical Center
Eduarda Fernandes - Universidade do Porto
Florian Fischer - Bielefeld University
Reza Fouladi Fard - College Station Medical Center
Paola M. Friedrich - St Jude Childrens Res Hosp, Dept Oncol, 332 N Lauderdale St, Memphis, TN 38105 USA
Takeshi Fukumoto - Gene
Getnet Azeze Gedefaw - Bahir Dar University
Ahmad Ghashghaee - Supreme Council Of Health
Asadollah Gholamian - College Station Medical Center
Arvin Haj-Mirzaian - University of Tehran
Arya Haj-Mirzaian - University of Tehran
Samer Hamidi - Supreme Council Of Health
James D. Harvey - University of Washington
Hamid Yimam Hassen - Mizan Tepi University
Simon Hay - University of Washington
Chi Linh Hoang - Trường ĐH Nguyễn Tất Thành
Michael K. Hole - Univ Texas Austin, Austin, TX 78712 USA
Nobuyuki Horita - NHGRI, NIH, Bethesda, MD 20892 USA
Seyyed Nasrollah Hosseini - Deputy Educ, Tehran, Iran
Mehdi Hosseinzadeh - Islamic Azad University, Tehran
Mohamed Hsairi - Supreme Council Of Health
Melissa Maria Hudson - St Jude Childrens Res Hosp, Dept Oncol, 332 N Lauderdale St, Memphis, TN 38105 USA
Kaire Innos - Biostat
Farzad Jalilian - Dev & Hlth Promot Res Ctr, Kermanshah, Iran
Spencer L. James - University of Washington
Amir Kasaeian - University of Tehran
Tesfaye Dessale Kassa - Clin Pharm Unit, Mekelle, Ethiopia
Nicholas J. Kassebaum - University of Washington
Peter Njenga Keiyoro - University of Nairobi
Yousef Saleh Khader - College Station Medical Center
Jagdish Khubchandani - Ball State University
Neda Kianipour - Dept Publ Hlth, Kermanshah, Iran
Jeannette Kirby - College Station Medical Center
Adnan Kisa - Kristiania Univ Coll, Dept Hlth Management & Hlth Econ, Oslo, Norway
Sezer Kisa - University of South Carolina
Jonathan M. Kocarnik - University of Washington
Paolo Lauriola - CNR, Inst Clin Physiol, Pisa, Italy
Alan D. Lopez - University of Washington
Margit Magi - Natl Inst Hlth Dev, Estonian Canc Registry, Dept Registries, Tallinn, Estonia
Manzoor Ahmad Malik - Indian Inst Technol, Dept Humanities & Social Sci, Roorkee, Haridwar, India
Ali Manafi - College Station Medical Center
Navid Manafi - College Station Medical Center
Mohammad Ali Mansournia - University of Tehran
Benjamin Ballard Massenburg - University of Washington
Varshil Mehta - College Station Medical Center
Hagazi Gebre Meles - Mekelle University
Tuomo J. Meretoja - Helsinki Univ Hosp, Breast Surg Unit, Helsinki, Finland
Tomislav Mestrovic - Dr Zora Profozic Polyclin, Clin Microbiol & Parasitol Unit, Zagreb, Croatia
Mehdi Mirzaei-Alavijeh - Dev & Hlth Promot Res Ctr, Kermanshah, Iran
Seyed Mostafa Mir
Dara K. Mohammad - Univ Salahaddin, Dept Biol, Erbil, Iraq
Aso Mohammad Darwesh - Univ Human Dev, Informat Technol Dept, Sulaimaniyah, Iraq
Naser Mohammad Gholi Mezerji - Biostat
Roghayeh Mohammadibakhsh - College Station Medical Center
Milad Mohammadoo-Khorasani - Tarbiat Modares University
Ali H. Mokdad - University of Washington
Yoshan Moodley - University of KwaZulu-Natal
Mahmood Moosazadeh - College Station Medical Center
Maryam Moossavi - College Station Medical Center
Farhad Moradpour - College Station Medical Center
Shane Douglas Morrison - University of Washington
Kindie Fentahun Muchie - University of Gondar
Mohsen Naghavi - University of Washington
Javad Nazari - Arak University
Josephine W. Ngunjiri - University of Embu
Cuong Tat Nguyen - Trường ĐH Nguyễn Tất Thành
Long Hoang Nguyen - Trường ĐH Nguyễn Tất Thành
Son Hoang Nguyen - Duy Tan University
Trang Huyen Nguyen - College Station Medical Center
Molly R. Nixon - University of Washington
Andrew T. Olagunju - McMaster University
Tinuke O. Olagunju - McMaster University
Sok King Ong - Univ Brunei Darussalam, Inst Hlth Sci, Gadong, Brunei
Keiu Paapsi - Biostat
Alyssa Pennini - University of Washington
David M. Pereira - Universidade do Porto
Julian David Pillay - Durban University of Technology
Mostafa Qorbani - College Station Medical Center
Mohammad Rabiee - Sharif University of Technology
Navid Rabiee - Amirkabir University of Technology
Samira Raoofi - Supreme Council Of Health
David Laith Rawaf - Imperial Coll London, Who Collaborating Ctr Publ Hlth Educ & Training, London, England
Salman Rawaf
Robert C. Reiner - University of Washington
Nima Rezaei - University of Tehran
Aziz Rezapour - College Station Medical Center
Kedir Teji Roba - Supreme Council Of Health
Les L. Robison - St Jude Childrens Res Hosp, Dept Epidemiol & Canc Control, 332 N Lauderdale St, Memphis, TN 38105 USA
Carlos Rodriguez-Galindo - St Jude Childrens Res Hosp, Dept Oncol, 332 N Lauderdale St, Memphis, TN 38105 USA
Gholamreza Roshandel - University of Tehran
Saeid Safiri - College Station Medical Center
Mohamadreza Salahshoor - College Station Medical Center
Saleh Salehi Zahabi - College Station Medical Center
Abdallah M. Samy - Ain Shams University
Milena M. Santric Milicevic - University of Belgrade
Maheswar Satpathy - Utkal University
Susan M. Sawyer - Dept Paediat, Melbourne, Qld, Australia
Seyedmojtaba Seyedmousavi - University of Tehran
Hosein Shabaninejad - College Station Medical Center
Masood Ali Shaikh
Amir Shamshirian - College Station Medical Center
Morteza Shamsizadeh - College Station Medical Center
Reza Shirkoohi - University of Tehran
Soraya Siabani - University of Technology Sydney
Jasvinder A. Singh - University of Alabama
Khairil Siramlee - Minist Hlth, Zagreb, Croatia
Rafael Tabares-Seisdedos - Universitat de València
Mohamad-Hani Temsah - King Saud University
Bach Xuan Tran - College Station Medical Center
Irfan Ullah - Gomal University
Amir Vahedian-Azimi - College Station Medical Center
Stein Emil Vollset - University of Washington
Theo Vos - University of Washington
Yasir Waheed - College Station Medical Center
Girmay Teklay Weldesamuel - Aksum University
Hailemariam Mekonnen Workie - Dept Neonatal & Pediat Hlth Nursing, Bahir Dar, Ethiopia
Rixing Xu - University of Washington
Mehdi Yaseri - University of Tehran
Naohiro Yonemoto - Natl Ctr Neurol & Psychiat, Dept Psychopharmacol, Tokyo, Japan
Chuanhua Yu - Oslo Univ Hosp, Dept Canc Immunol, Oslo, Norway
Vesna Zadnik - Inst Oncol Ljubljana, Epidemiol & Canc Registry Sect, Ljubljana, Slovenia
Telma Zahirian Moghadam - College Station Medical Center
Zoubida Zaidi - Univ Hosp Setif, Dept Epidemiol, Setif, Algeria
Alireza Zangeneh - Dev & Hlth Promot Res Ctr, Kermanshah, Iran
Taye Abuhay Zewale - Biostat
Arash Ziapour - College Station Medical Center
Sanjay Zodpey - Indian Inst Publ Hlth, Gandhinagar, India
Christopher J. L. Murray - University of Washington
Christina Fitzmaurice - University of Washington
Nickhill Bhakta - St Jude Childrens Res Hosp, Dept Oncol, 332 N Lauderdale St, Memphis, TN 38105 USA
GBD 2017 Childhood Canc Collaborat
Publication Details: The lancet oncology, Vol.20(9), pp.1211-1225
Publisher: Elsevier
Number of pages: 15
Grant note: Cancer Foundation Finland sr US National Institutes of Health (NIH) Loan Repayment Program; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA Egyptian Fulbright Mission Program (EFMP) Division of Intramural Research, National Institute of Allergy and Infectious Diseases (NIAID), NIH, Bethesda, MD, USA POCI/01/0145/FEDER/007728; POCI/01/0145/FEDER/007265 / European Union (FEDER funds); European Commission American Lebanese Syrian Associated Charities (ALSAC) St Baldrick's Foundation 180129; 160100 / Cancer Foundation Finland sr Bill AMP; Melinda Gates Foundation; CGIAR Department of Science and Technology, Government of India, New Delhi, through the INSPIRE Faculty program 175087 / Ministry of Education, Science and Technological Development, Republic of Serbia PROMETEOII/2015/021 / Generalitat Valenciana; Center for Forestry Research & Experimentation (CIEF) PI17/00719 / ISCIII-FEDER; Spanish Government PT2020 UID/MULTI/04378/2013; PT2020 UID/QUI/50006/2013 / National Funds (FCT/MEC, Fundacao para a Ciencia e a Tecnologia and Ministerio da Educacao e Ciencia); Fundacao para a Ciencia e a Tecnologia (FCT)
Identifiers: 9932596008331
Academic Unit: University Ha'il
Language: English
Resource Type: Journal article