Abstract
Secondary and tertiary amines
6 are conveniently prepared in good yields by reacting organozinc halides with adducts
4, which are derived from the corresponding amines, aldehydes and benzotriazole. The use of organozinc reagents enables the introduction of nitro, cyano or ester functionalities into amine mainframes. This methodology was also used to prepare functionalized amides
8.
The reactions of organozinc halides with benzotriazole derivatives
1 enable the introduction of nitro, cyano or ester functionalities into secondary and tertiary amine or amide mainframes
2.