The present and future disease burden of hepatitis C virus infections with today's treatment paradigm - volume 3

A Sibley; K H Han; A Abourached; L A Lesmana; M Makara; W Jafri; R Salupere; A M Assiri; A Goldis; F Abaalkhail; Z Abbas; A Abdou; F Al Braiki; F Al Hosani; K Al Jaberi; M Al Khatry; M A Al Mulla; H Al Quraishi; A Al Rifai; Y Al Serkal; A Alam; S M Alavian; H I Alashgar; S Alawadhi; L Al-Dabal; P Aldins; F Z Alfaleh; A S Alghamdi; R Al-Hakeem; A A Aljumah; A Almessabi; A N Alqutub; K A Alswat; I Altraif; M Alzaabi; N Andrea; M A Babatin; A Baqir; M T Barakat; O M Bergmann; A R Bizri; S Blach; A Chaudhry; M S Choi; T Diab; S Djauzi; E S El Hassan; S El Khoury; C Estes; S Fakhry; J I Farooqi; H Fridjonsdottir; R A Gani; A Ghafoor Khan; L Gheorghe; M Gottfredsson; S Gregorcic; J Gunter; B Hajarizadeh; S Hamid; I Hasan; A Hashim; G Horvath; B Hunyady; R Husni; A Jeruma; J G Jonasson; B Karlsdottir; D Y Kim; Y S Kim; Z Koutoubi; V Liakina; Y S Lim; A Löve; M Maimets; R Malekzadeh; M Matičič; M S Memon; S Merat; J E Mokhbat; F H Mourad; D H Muljono; A Nawaz; N Nugrahini; S Olafsson; S Priohutomo; H Qureshi; P Rassam; H Razavi; D Razavi-Shearer; K Razavi-Shearer; B Rozentale; M Sadik; K Saeed; A Salamat; F M Sanai; A Sanityoso Sulaiman; R A Sayegh; A I Sharara; M Siddiq; A M Siddiqui; G Sigmundsdottir; B Sigurdardottir; D Speiciene; A Sulaiman; M A Sultan; M Taha; J Tanaka; H Tarifi; G Tayyab; I Tolmane; M Ud Din; M Umar; J Valantinas; J Videčnik-Zorman; C Yaghi; E Yunihastuti; M A Yusuf; B F Zuberi; J D Schmelzer

doi:10.1111/jvh.12476

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The present and future disease burden of hepatitis C virus infections with today's treatment paradigm - volume 3

Journal article

Open access

Peer reviewed

The present and future disease burden of hepatitis C virus infections with today's treatment paradigm - volume 3

A Sibley, K H Han, A Abourached, L A Lesmana, M Makara, W Jafri, R Salupere, A M Assiri, A Goldis, F Abaalkhail, …

Journal of viral hepatitis, Vol.22 Suppl 4(S4), pp.21-41

12/2015

DOI: https://doi.org/10.1111/jvh.12476

PMID: 26513446

Abstract

Adolescent

Adult

Aged

Aged, 80 and over

Cost of Illness

Female

Global Health

Hepacivirus - isolation & purification

Hepatitis C, Chronic - epidemiology

Hepatitis C, Chronic - mortality

Hepatitis C, Chronic - therapy

Hepatitis C, Chronic - virology

Humans

Incidence

Male

Middle Aged

Models, Statistical

Prevalence

Survival Analysis

Viremia - epidemiology

Viremia - mortality

Viremia - therapy

Viremia - virology

Young Adult

The total number, morbidity and mortality attributed to viraemic hepatitis C virus (HCV) infections change over time making it difficult to compare reported estimates from different years. Models were developed for 15 countries to quantify and characterize the viraemic population and forecast the changes in the infected population and the corresponding disease burden from 2014 to 2030. With the exception of Iceland, Iran, Latvia and Pakistan, the total number of viraemic HCV infections is expected to decline from 2014 to 2030, but the associated morbidity and mortality are expected to increase in all countries except for Japan and South Korea. In the latter two countries, mortality due to an ageing population will drive down prevalence, morbidity and mortality. On the other hand, both countries have already experienced a rapid increase in HCV-related mortality and morbidity. HCV-related morbidity and mortality are projected to increase between 2014 and 2030 in all other countries as result of an ageing HCV-infected population. Thus, although the total number of HCV countries is expected to decline in most countries studied, the associated disease burden is expected to increase. The current treatment paradigm is inadequate if large reductions in HCV-related morbidity and mortality are to be achieved.

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Title: The present and future disease burden of hepatitis C virus infections with today's treatment paradigm - volume 3
Creators - without role: A Sibley - Center for Disease Analysis
K H Han - Yonsei University
A Abourached - Ministry of Public Health
L A Lesmana - Rumah Sakit Umum Pusat Nasional Dr. Cipto Mangunkusumo
M Makara - Unified Szent István and Szent László Hospital
W Jafri - Aga Khan University
R Salupere - Tartu University Hospital
A M Assiri - Ministry of Health
A Goldis - Victor Babeș University of Medicine and Pharmacy Timișoara
F Abaalkhail - King Faisal Specialist Hospital & Research Centre
Z Abbas - Ziauddin University
A Abdou - Dubai Health Authority
F Al Braiki - Abu Dhabi Health Services
F Al Hosani - Abu Dhabi Health Services
K Al Jaberi - Abu Dhabi Health Services
M Al Khatry - American University of Ras Al Khaimah
M A Al Mulla - Abu Dhabi Health Services
H Al Quraishi - Dubai Health Authority
A Al Rifai - Mafraq Hospital
Y Al Serkal - Hospitals Sector, Ministry of Health, Abu Dhabi, UAE
A Alam - Shaikh Zayed Hospital
S M Alavian - Baqiyatallah University of Medical Sciences
H I Alashgar - King Faisal Specialist Hospital & Research Centre
S Alawadhi - Dubai Health Authority
L Al-Dabal - Dubai Health Authority
P Aldins - Pauls Stradiņš Clinical University Hospital
F Z Alfaleh - King Saud University
A S Alghamdi - King Fahd Medical City
R Al-Hakeem - Ministry of Health
A A Aljumah - King Saud bin Abdulaziz University for Health Sciences
A Almessabi - Abu Dhabi Health Services
A N Alqutub - King Fahd Medical City
K A Alswat - King Saud University
I Altraif - King Saud bin Abdulaziz University for Health Sciences
M Alzaabi - Zayed Military Hospital
N Andrea - Abu Dhabi Health Services
M A Babatin - King Fahd Medical City
A Baqir - Nishtar Medical College and Hospital
M T Barakat - Abu Dhabi Health Services
O M Bergmann - National University Hospital of Iceland
A R Bizri - American University of Beirut Medical Center
S Blach - Center for Disease Analysis
A Chaudhry - GIFT University
M S Choi - Sungkyunkwan University
T Diab - Al Ain Hospital
S Djauzi - Rumah Sakit Umum Pusat Nasional Dr. Cipto Mangunkusumo
E S El Hassan - Dubai Health Authority
S El Khoury - University of Balamand
C Estes - Center for Disease Analysis
S Fakhry - Abu Dhabi University
J I Farooqi - Khyber Medical University
H Fridjonsdottir - National University Hospital of Iceland
R A Gani - Rumah Sakit Umum Pusat Nasional Dr. Cipto Mangunkusumo
A Ghafoor Khan - Lady Reading Hospital
L Gheorghe - Institutul Clinic Fundeni
M Gottfredsson - National University Hospital of Iceland
S Gregorcic - Ljubljana University Medical Centre
J Gunter - Center for Disease Analysis
B Hajarizadeh - UNSW Sydney
S Hamid - Aga Khan University
I Hasan - Rumah Sakit Umum Pusat Nasional Dr. Cipto Mangunkusumo
A Hashim - King Faisal Specialist Hospital & Research Centre
G Horvath - Buda Health Center
B Hunyady - Somogy Megyei Kaposi Mór Oktató Kórház
R Husni - University Medical Center Rizk Hospital
A Jeruma - Riga Stradiņš University
J G Jonasson - National University Hospital of Iceland
B Karlsdottir - National University Hospital of Iceland
D Y Kim - Yonsei University
Y S Kim - Bucheon University
Z Koutoubi - Cleveland Clinic
V Liakina - Vilnius University
Y S Lim - University of Ulsan
A Löve - National University Hospital of Iceland
M Maimets - Tartu University Hospital
R Malekzadeh - Tehran University of Medical Sciences
M Matičič - Ljubljana University Medical Centre
M S Memon - Asian Institute of Medical Science (AIMS), Hyderabad, Sindh, Pakistan
S Merat - Tehran University of Medical Sciences
J E Mokhbat - University Medical Center Rizk Hospital
F H Mourad - American University of Beirut Medical Center
D H Muljono - Eijkman Institute for Molecular Biology
A Nawaz - Department of Gastroenterology, Fatima Memorial Hospital College of Medicine and Dentistry, Lahore, Pakistan
N Nugrahini - Ministry of Health
S Olafsson - National University Hospital of Iceland
S Priohutomo - Ministry of Health
H Qureshi - Pakistan Health Research Council
P Rassam - University of Balamand
H Razavi - Center for Disease Analysis
D Razavi-Shearer - Center for Disease Analysis
K Razavi-Shearer - Center for Disease Analysis
B Rozentale - Riga Stradiņš University
M Sadik - Asian Institute of Medical Science (AIMS), Hyderabad, Sindh, Pakistan
K Saeed - Khawar Clinic, Sahiwal, Pakistan
A Salamat - Military Hospital
F M Sanai - King Saud University
A Sanityoso Sulaiman - University of Indonesia
R A Sayegh - Saint Joseph University
A I Sharara - American University of Beirut Medical Center
M Siddiq - Rawalpindi Medical University
A M Siddiqui - Allama Iqbal Medical College
G Sigmundsdottir - Directorate of Health
B Sigurdardottir - National University Hospital of Iceland
D Speiciene - Vilnius University
A Sulaiman - Klinik Hati Prof. Ali Sulaiman, Jakarta, Indonesia
M A Sultan - Health Funding Department, Enaya Insurance Company, Abu Dhabi, UAE
M Taha - Tawam Hospital
J Tanaka - Hiroshima University
H Tarifi - Tawam Hospital
G Tayyab - Doctors Hospital and Medical Center, Lahore, Pakistan
I Tolmane - Riga Stradiņš University
M Ud Din - Pakistan Society of Gastroenterology, Karachi, Pakistan
M Umar - Department of Medicine, Holy Family Hospital, Rawalpindi, Pakistan
J Valantinas - Vilnius University
J Videčnik-Zorman - Clinic for Infectious Diseases and Febrile Illnesses, University Medical Centre, Ljubljana, Slovenia
C Yaghi - Saint Joseph University
E Yunihastuti - Faculty
M A Yusuf - Shaukat Khanum Memorial Cancer Hospital & Research Centre, Lahore, Pakistan
B F Zuberi - Dow Medical College, Karachi, Pakistan
J D Schmelzer - Center for Disease Analysis
Publication Details: Journal of viral hepatitis, Vol.22 Suppl 4(S4), pp.21-41
Identifiers: 9913465008331
Academic Unit: King Faisal University; Alfaisal University; King Abdulaziz University; King Saud University; Dar Al Uloom University; King Saud Bin Abdulaziz University for Health Sciences
Language: English
Resource Type: Journal article