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The role of BRCA1/2 in hereditary and familial breast and ovarian cancers
Journal article   Open access  Peer reviewed

The role of BRCA1/2 in hereditary and familial breast and ovarian cancers

Yousef M. Hawsawi, Nouf S. Al-Numair, Turki M. Sobahy, Areej M. Al-Ajmi, Raneem M. Al-Harbi, Mohammed A. Baghdadi, Atif A. Oyouni and Osama M. Alamer
Molecular genetics & genomic medicine, Vol.7(9), pp.e879-n/a
09/2019
DOI: https://doi.org/10.1002/mgg3.879
PMCID: PMC6732305
PMID: 31317679

Abstract

BRCA1 BRCA2 breast cancer founder effect genetics Review variant
BRCA1/2 pathogenic variants have become associated with familial breast and ovarian cancers, and hereditary cancer‐predisposition syndrome. With advances in molecular biology, BRCA profiling facilitates early diagnosis and the implementation of preventive and therapeutic strategies.
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https://doi.org/10.1002/mgg3.879View
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