Abstract
High yielding synthesis of six- and five-membered
N-substituted iminosugar glycosides and of five-membered iminosugar thioglycosides by nucleophilic opening of both new and previously described
N-diethoxycarbonylvinyl anhydroiminosugar derivatives (glycosyl donors) with primary alcohols, primary thiols, and thiophenol (glycosyl acceptors) is reported. The reactions are highly stereoselective, with anomeric ratios better than 4:1.
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