Abstract
A new chalcone series has been developed that may be useful in the treatment of lung cancer. The new series was confirmed by the different spectral tools. MTT assay was used to detect the cytotoxic effect of the novel chalcones against lung cancer cell line (A549). Molecular docking studies were performed on the most two effective chalcones
7b
and
7c
. Different molecular techniques were utilized to study the activity and the effect of two chalcones
7b
and
7c
on apoptosis of A549 cell line.