Abstract
Microfluidics points to the manner of fluids at micro- and nano-scales levels. This research aims to find the heat transfer rate of hydroxyapatite bio-ceramic and its composite (HA/carbon nanotube) to find the optimized volume fraction for the human blood plasma through the vessel micro-flow. It can also be used in the teeth reach extreme temperatures, causing the tooth thermal pain. To find the answer, the body condition through time was considered. Thus, simulated body fluid, which acts as an adhesive to bond artificial materials to living bones, was chosen as the solution close to mouth-environment. Hydroxyapatite is a ceramic-based material which has bioactivity and biocompatibility. However, carbon nanotube, which is a carbon-based material, has high tensile strength and stiffness, that could likely be utilized to reinforce hydroxyapatite. The results showed that heat transfer rate for hydroxyapatite bio-ceramic dispersed in simulated body fluid solution in 1, 14 and 28 days, decreased − 14.8785%, − 15.4279% and − 17.4450%, respectively; thus, time effect was 2.5965%. Also, heat transfer rate for HA/carbon nanotube dispersed in simulated body fluid solution in 1, 14 and 28 days enhanced 25.1189%, 25.6410% and 25.7923%, respectively; thus, time effect was 0.6734%. This study proved that time can affect the heat transfer rate in simulated body fluid solution.