Total synthesis of cyclic heptapeptide Rolloamide B

Mirna El Khatib; Mohamed Elagawany; Eray Caliskan; Emily Faith Davis; Hassan M. Faidallah; Said A. El-feky; Alan R. Katritzky

doi:10.1039/c3cc39291k

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Total synthesis of cyclic heptapeptide Rolloamide B

Journal article

Peer reviewed

Total synthesis of cyclic heptapeptide Rolloamide B

Mirna El Khatib, Mohamed Elagawany, Eray Caliskan, Emily Faith Davis, Hassan M. Faidallah, Said A. El-feky and Alan R. Katritzky

Chemical communications (Cambridge, England), Vol.49(26), pp.2631-2633

04/04/2013

DOI: https://doi.org/10.1039/c3cc39291k

PMID: 23435737

Abstract

Chemistry

Chemistry, Multidisciplinary

Physical Sciences

Science & Technology

The first total synthesis of Rolloamide B, a cyclic proline-enriched heptapeptide, is reported. This work features solution phase benzotriazole-mediated peptide synthesis ligating native amino acids.

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Title: Total synthesis of cyclic heptapeptide Rolloamide B
Creators - without role: Mirna El Khatib - University of Florida
Mohamed Elagawany - University of Florida
Eray Caliskan - University of Florida
Emily Faith Davis - Univ Florida, Dept Chem, Ctr Heterocycl Cpds, Gainesville, FL 32611 USA
Hassan M. Faidallah - King Abdulaziz University
Said A. El-feky - Zagazig University
Alan R. Katritzky - University of Florida
Publication Details: Chemical communications (Cambridge, England), Vol.49(26), pp.2631-2633
Publisher: Royal Soc Chemistry
Number of pages: 3
Grant note: University of Florida Kenan foundation King Abdulaziz University
Identifiers: 9919261808331
Academic Unit: Northern Borders University; King Abdulaziz University
Language: English
Resource Type: Journal article