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Towards an Efficient Preparation of Hydromorphone
Journal article   Peer reviewed

Towards an Efficient Preparation of Hydromorphone

Rene Csuk, Galina Vasileva and Alexander Barthel
Synthesis (Stuttgart), Vol.44(18), pp.2840-2842
17/09/2012

Abstract

Chemistry Chemistry, Organic Physical Sciences Science & Technology
Dihydromorphone was prepared from morphine in high yield, excellent purity, and low residual metal content. The key steps used palladium on porous glass and a modified Oppenauer oxidation, or Wilkinson's catalyst.

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