Abstract
Amyloidosis is an uncommon disease, which affects multiple body organs. Localized forms of amyloidosis can involve the lung in various ways. Of these, tracheobronchial amyloidosis (TBA) is the most common but still a rare entity. TBA has diverse manifestations and may present insidiously. This may lead to misdiagnosis and may delay the diagnosis in presence of other chronic respiratory diseases. Although TBA is a localized disease process, the course may not be benign and varies according to the degree of involvement. Different treatment modalities have been attempted such as bronchoscopic debridement and debulking, external beam radiation therapy (EBRT), and laser ablation, but there is currently no fully effective treatment. Herein, we describe two cases of TBA with differing presentations, to draw attention to this uncommon entity, its clinical presentation, and available management.