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Triphenyl borate catalyzed synthesis of amides from carboxylic acids and amines
Journal article   Peer reviewed

Triphenyl borate catalyzed synthesis of amides from carboxylic acids and amines

Seema A. Ghorpade, Dinesh N. Sawant and Nagaiyan Sekar
Tetrahedron, Vol.74(48), pp.6954-6958
29/11/2018

Abstract

Chemistry Chemistry, Organic Physical Sciences Science & Technology
Herein we report triphenyl borate as a new catalyst for synthesis of amides by catalytic condensation of carboxylic acids and amines. Our protocol is applicable for synthesis of wide range of amides furnishing excellent yields up to 92%. In addition developed method requires low catalyst loading, short time, less amount of solvent, works under air atmosphere and notably no need of azeotropic reflux using special Dean Stark apparatus or molecular sieves. (C) 2018 Elsevier Ltd. All rights reserved.

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