Abstract
In the course of our studies on the chemical constituents of the leaves of Skimmia laureola [26], a new triterpene O -methyl cyclolaudenol ( 1 ) and a new coumarin, (+)-7-methoxy-6-(2' R -methoxy-3'-hydroxy-3'-methyl butyl) coumarin ( 2 ) were isolated. In addition five known coumarins, isogospherol ( 3 ), heraclenol ( 4 ), 5,8-dimethoxy coumarin-2 H -1-benzopyran-2-one ( 5 ), 7-methoxy-6[2'-oxo-3'-methyl butyl] coumarin ( 6 ), and (+)-ulopterol ( 7 ) were also isolated for the first time from this plant. The structures were identified by spectroscopic studies and the stereochemistry at C-2' in compounds 3 and 4 were established by Horeau's procedure.