Abstract
Recently increased attention is being paid to most aluminum compound due to their serious effects on the energy metabolism and hematology, fertility and reproduction. Natural products are good options when treating heavy metals toxicity because of their effectiveness, fewer side effects and relatively low cost. The study was made on 336(8 weeks old) male albino Wistar rats (weighing between 150-200 g). The animals were given a dose of Aluminum Chloride (AlCl3) (30mg/kg) every other day intraperitoneally for eight weeks, and a dose of Turmeric (Curcuma Longa) (4mg/kg) daily intraperitoneally for eight weeks. The following parameters were measured in blood serum: glucose, total protein, albumin, total cholesterol, triglycerides, bilirubin, alkaline phosphatase (ALP), aspartate amino transferase (AST), alanine amino transferase (ALT), gamma glutamyl transferase (GGT). Aluminum Chloride caused an increase in serum glucose levels, total cholesterol and triglycerides, bilirubin, ALP, AST, ALT and GGT. Aluminum Chloride caused a decrease of total protein and albumin level, and caused hepatocytic degenerations and necrosis in addition to severe vascular congestion, especially in the portal blood vessel in the liver, while Curcuma Longa ameliorates these effects near to their normal values.