Abstract
The transition metal tungstates have attracted and gained much interest in recent years because of the excellent electrocatalytic properties. Herein, we have explored the electrochemical activity of a copper tungstate nanosheet (CuW NSs) modified glassy carbon electrode (CuW NSs/GC electrode) toward the detection of the anti-inflammatory drug mesalazine (MSA). The successful formation of CuW NSs was concluded from different analytical and spectroscopic methods. The CuW NSs modified GC electrode demonstrated superior electrocatalytic activity toward the MSA detection with a lower peak potential at +0.33 V. The constructed electrochemical sensor for the detection of MSA showed a good sensitivity (1.2 μA μM–1 cm–2), wide working range (0.005–367 μM), and trace level detection limit (0.0012 μM). Moreover, it is worth noting that the CuW NSs not only enhaced activity but also promoted the electron transfer rate. The proposed sensor was evaluated for its real-time applications to the detection of MSA in human urine samples, and in good satisfactory results were obtained.