Abstract
Lupus nephritis is particularly a very concerning occurrence due to the susceptibility for potential renal damage and ultimately renal failure. Cardiac involvement was present as well in the form of pericarditis. Our study reports a case of lupus nephritis that has had a very severe course of fluctuations between relapses and improvements which constantly necessitated an MDT interference at various points.
We report a case of a 13-year-old female patient who presented with a 5-day history of fever, dizziness, joint pain, menorrhagia, convulsions, and visual disturbances. Essential diagnostic tests took place and a diagnosis of lupus nephritis was confirmed.
In conclusion we found that a combination of various treatment modalities and flexibility in decision making in response to changes in the clinical course are vital to treatment success. Utilization of plasma exchange which resulted in an enormous drop in the percentage of fragmented red blood cells (RBCs) from 9.8% to 1.8%.
•The combination of lupus nephritis, atypical hemolytic syndrome, and pericarditis is a very rare and occasional finding.•A wide range of complications can occur rapidly which require a constant multidisciplinary team availability.•Utilization of plasma exchange resulted in a significant reduction of the fragmented RBCs percentage from 9.8% to 1.8%.•Eculizumab usage was essential, the dose used was 900 mg IV weekly for 4 weeks, followed by a fifth dose of 1200 mg IV followed by a 1200 mg IV every 2 weeks after a highly specialized nephrology team involvement.