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UK-2A, B, C and D, novel antifungal antibiotics from Streptomyces sp 517-02 .1. Fermentation, isolation, and biological properties
Journal article   Open access  Peer reviewed

UK-2A, B, C and D, novel antifungal antibiotics from Streptomyces sp 517-02 .1. Fermentation, isolation, and biological properties

M Ueki, K Abe, M Hanafi, K Shibata, T Tanaka and M Taniguchi
Journal of antibiotics, Vol.49(7), pp.639-643
01/07/1996
DOI: https://doi.org/10.7164/antibiotics.49.639
PMID: 8784423

Abstract

Biotechnology & Applied Microbiology Immunology Life Sciences & Biomedicine Microbiology Pharmacology & Pharmacy Science & Technology
Novel antifungal antibiotics, UK-2A, B and a mixture of C and D, were obtained from the mycelial cake of Streptomyces sp. 517-02. All of the UK-2 compounds were similar in structure to antimycin A. The antifungal activities of UK-2 compunds were as strong as that of antimycin A. However, the UK-2 compounds demonstrated weak cytotoxicity compared to antimycin A.
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https://doi.org/10.7164/antibiotics.49.639View
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