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Ultrasensitive chemiluminescent immunoassay labeled with graphene oxide
Journal article   Peer reviewed

Ultrasensitive chemiluminescent immunoassay labeled with graphene oxide

Yinhuan Song, Taoyi Yang, Tonghuan Zhang, Nan Jin, Yanjun Zhao and Aiping Fan
Analytical methods, Vol.5(15), pp.3646-3649
01/01/2013
DOI: https://doi.org/10.1039/c3ay40737c

Abstract

Chemistry Chemistry, Analytical Food Science & Technology Life Sciences & Biomedicine Physical Sciences Science & Technology Spectroscopy Technology
Graphene oxide (GO) was for the first time designed as a bionano-label for sensitive chemiluminescent (CL) immunosensing of human IgG by taking advantage of a magnetic separation-mixing process and a GO-triggered luminol-H2O2 CL reaction. The detection limit of the concentration of human IgG is 1.2 pg mL(-1), which is comparable with or better than other immunoassays.

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