Abstract
Schematic illustration of the developed analytical procedure. I) Synthesis of the US-MagMIP; II) (A) Rebinding process between BPA and US-MagMIP (B) separation of US-MagMIP from the solution and throw the supernatant (C) Elution of BPA using phosphate buffer containing 20% of methanol (D) Drop-casting of 60 μL of the residual concentration of BPA on the surface of AuNPs/CBNPs/SPCE; III) Electrochemical detection of BPA using the developed sensor.
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•A simple and rapid method for monitoring BPA in water samples was developed.•The US-magMIP combined with SPCE modified CBNPs and AuNPs was used.•The electrochemical sensing approach exhibits a highly selective and sensitive detection towards BPA.
Sample preparation is considered as one of the most interesting applications of magnetic molecularly imprinted polymer (MagMIP) used as adsorbents for various compounds prior to their determination using the developed analytical techniques. In this context, we present in this paper a developed Ultrasound-assisted magnetic molecularly imprinted polymer (US-MagMIP) combined to an electrochemical sensor modified with a nanocomposite of carbon black nanoparticles (CBNPs), and Gold nanoparticles (AuNPs) for highly selective and sensitive detection of Bisphenol A (BPA). The electrochemical characterization of the developed sensor was investigated by electrochemical impedance spectroscopy and cyclic voltammetry. Various parameters were optimized such as the effect of voltammetric mode, the effect of pH, the amount of US-MagMIP and the rebinding time. The electrochemical sensor exhibits a high sensitivity for BPA with a LOD of 8.8 nM with a wide linear range from 0.07 μM to 10 μM. Moreover, this sensor provides a high selectivity towards various likely interferents by combination with US-MagMIP prior to analysis. The developed analytical approach was applied successfully for determination of BPA in Tap and mineral water samples.