Abstract
Pantoprazole drug residue is present in some water bodies leading to toxicity to human beings. The uptake of pantoprazole drug residue from water is reported on composite iron nano adsorbent. Adsorbent was prepared by green method and characterized by FTIR, XRD, SEM, TEM and EDX techniques. The pantoprazole concentrations in adsorption experiments were determined by HPLC on new generation Sunshell C18 column (150×4.61mm; 2.6μm). The optimized parameters were 30.0min., 50μgL−1, 7.0, 1.0gL−1, and 25.0°C as contact time, concentration, pH, adsorbent amounts and temperature. The data obeyed Langmuir, Freundlich, Temkin and Dubinin–Radushkevich isotherms. ΔG° values were −9.53, −9.57 and −9.62kJ/mol at 20, 25 and 30°C temperatures. ΔH° and ΔS° values were −3.39 and 20.19×10−3. These magnitudes showed favorable and exothermic adsorption. Pseudo-first-order and liquid film diffusion mechanisms of the adsorption were reported. The reported adsorption method was fast, environmental friendly and low-priced due to its nature to be applicable under natural conditions of water resources. The developed method may be applicable for the removal of pantoprazole drug residue in natural water resources at pH7.0 with low amount of adsorbent and contact time. The adsorption method may be used for pantoprazole removal from any water body at large and economic scale.
•Green synthesis of composite iron nano adsorbent (new generation adsorbent).•Developed method is speedy, environmental friendly and inexpensive.•Method work at natural water pH with low contact time.