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Utility of cyano-N-(2-oxo-1,2-dihydroindol-3-ylidene)acetohydrazide in the synthesis of novel heterocycles
Journal article   Peer reviewed

Utility of cyano-N-(2-oxo-1,2-dihydroindol-3-ylidene)acetohydrazide in the synthesis of novel heterocycles

Mahmoud R. Mahmoud, Ahmed K. El-Ziaty, Fatma S. M. Abu El-Azm, Mahmoud F. Ismail and Sayed A. Shiba
Journal of chemical research, Vol.37(2), pp.80-85
01/02/2013

Abstract

Chemistry Chemistry, Multidisciplinary Physical Sciences Science & Technology
Cyano-N-(2-oxo-1,2-dihydroindol-3-ylidene)acetohydrazide was prepared by condensation of isatin with cyanoacetohydrazide in refluxing 1,4-dioxane. Subsequent reaction with a variety of electrophilic and nucleophilic reagents afforded novel heterocyclic compounds and spirooxoindoles. The IR, H-1 NMR and mass spectra of all the synthesised compounds are discussed.

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