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Viral RNA-polymerases--a predicted 2'-O-ribose methyltransferase domain shared by all Mononegavirales
Journal article   Peer reviewed

Viral RNA-polymerases--a predicted 2'-O-ribose methyltransferase domain shared by all Mononegavirales

Francois Ferron, Sonia Longhi, Bernard Henrissat and Bruno Canard
Trends in biochemical sciences (Reference ed.), Vol.27(5), p.222
01/05/2002

Abstract

Biochemistry Ribonucleic acid RNA Viruses
Ferron et al present a computational analysis of the C-terminal region of RNA-dependent RNA-polymerases from Mononegavirales. Using a combination of sequence similarity and threading analysis, a 2'-O-ribose methyltransferase domain was identified that is involved in the capping of viral mRNAs.

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