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Virus-like particles as vaccines and vessels for the delivery of small molecules
Journal article   Peer reviewed

Virus-like particles as vaccines and vessels for the delivery of small molecules

Robert L Garcea and Lutz Gissmann
Current opinion in biotechnology, Vol.15(6), pp.513-517
01/12/2004
PMID: 15560977

Abstract

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Virus-like particles (VLPs) structurally mimic the viral capsid and have therefore been extensively, and quite successfully, used as vaccine and viral serology reagents. The ability of VLPs to include nucleic acids and small molecules has also made them novel vessels for gene and drug delivery. The regular, repetitive surface of VLPs has been exploited as a template for nanoscale synthesis. Recent progress has been made in the development of several virus models.

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