Abstract
The weak-strong uniqueness for Maxwell-Stefan systems and some generalized systems is proved. The corresponding parabolic cross-diffusion equations are considered in a bounded domain with no-flux boundary conditions. The key points of the proofs are various inequalities for the relative entropy associated with the systems and the analysis of the spectrum of a quadratic form capturing the frictional dissipation. The latter task is complicated by the singular nature of the diffusion matrix. This difficulty is addressed by proving its positive definiteness on a subspace and using the Bott-Duffin matrix inverse. The generalized Maxwell-Stefan systems are shown to cover several known cross-diffusion systems for the description of tumor growth and physical vapor deposition processes.