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ZnCl2 and Pd/C catalyzed synthesis of 2-substituted indoles
Journal article   Peer reviewed

ZnCl2 and Pd/C catalyzed synthesis of 2-substituted indoles

Atiur Ahmed, Munmun Ghosh, Pompy Sarkar and Jayanta K. Ray
Tetrahedron letters, Vol.54(49), pp.6691-6694
04/12/2013
DOI: https://doi.org/10.1016/j.tetlet.2013.09.061

Abstract

Chemistry Chemistry, Organic Physical Sciences Science & Technology
A facile, mild, efficient, and copper-free method has been developed for the synthesis of 2-substituted indoles via domino Sonogashira coupling/cyclization reaction catalyzed by ZnCl2 and palladium on carbon with simultaneous formations of C-C and C-N bonds. (C) 2013 Elsevier Ltd. All rights reserved.

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